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Daniel Konstantinov
Daniel Konstantinov

Difficult To Cure !!TOP!!



Yet despite all that progress, a wholesale "cure for cancer" remains elusive for many reasons. The first issue is that cancer is not just one disease that could be eradicated with one cure. Instead, it's hundreds of diseases, Siegel explained. "We would need hundreds of different types of cures to cure all cancer," she said.




Difficult To Cure !!TOP!!


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Another reason it's hard to cure cancer is that the bar for cancer being cured is incredibly high. Cancer is cured if there are no traces of it in the body and it will never come back or is not expected to come back. But even when all traces of a cancer have disappeared, there's no way of knowing with certainty that it won't return.


Toenails are made up of multiple layers stacked on top of each other. Toenail fungus can be tough to get rid of because it can get into and in between those layers. It may also sit on top of the nail or grow underneath it. In some cases, fungus can get into the cells that make the nail, called the nail matrix. That can make the fungus very difficult to eliminate because the cells manufacturing the rest of the toenail are infected.


Approximately 7,000 rare diseases affect 350-500 million people worldwide. The majority of these (80%) are monogenic, so-called because these genetic disorders are caused by a mutation in a single gene. While gene therapy holds great promise for the treatment of monogenic diseases in the future, efforts to find cures to date with traditional pharmaceuticals have resulted in treatments for only 5% of all rare diseases. Why has it been so difficult to find rare disease cures?


The exact definition of a rare disease varies by country, but no matter the definition, rare diseases affect 1% or less of the global population. Since there are many rare diseases within that 1%, the population for any one disease is very small. Because those affected are located around the world, they are unknown to one another or to those conducting rare disease research. The geographic spread, combined with the small number of people affected, has made it difficult to gain recognition as a population in need of a cure.


2. Phenylketonuria (PKU) affects various ethnic groups and geographic regions worldwide. In the United States, it occurs in 1 in 10,000 to 15,000 newborns. All newborns are tested for PKU within 72 hours after birth with a simple heel prick to generate the small amount of blood needed for the simple test for PKU. It is essential to identify those infants at risk for PKU, so that they can be started on an effective treatment and eat a diet that limits foods containing phenylalanine during infancy. As they grow older, they must avoid foods that are high in protein. Failure to follow these guidelines results in intellectual disabilities caused by a buildup of the amino acid phenylalanine, which is toxic to the nervous system. There is currently no cure for this debilitating disease, although American Gene Technologies (AGT) is working toward a cure for PKU.


3. Cystic Fibrosis affects about 30,000 in the United States. and more than 70,000 people worldwide. Until recently, attempts to deliver a working copy of the gene necessary to a cure have not been effective. With advances in viral vectors, this is changing. In 2019, the Cystic Fibrosis Foundation announced $500 million in funding over the next six years for research into treatments for cystic fibrosis. These include gene therapy strategies.


4. Hemophilia A affects an estimated 400,000 males worldwide, with about 20,000 in the United States. There is currently no cure for this genetic disease. In August 2020, the U.S. Food and Drug Administration (FDA) rejected a gene therapy called Roctavian and asked BioMarin Pharmaceutical for more evidence that the treatment is durable enough to justify use in patients by proving a long-lasting effect on bleeding rates that will not wear off, resulting in a return to the current standard of care for patients.


5. Muscular Dystrophy (MD) The most common forms in children, Duchenne and Becker, affect approximately 1 in every 5,600 to 7,700 males ages 5 to 24. There is currently no known cure for this genetic disease. However, the use of CRISPR gene-editing technology may lead to a long-awaited cure or treatment options.


Dyslexia is a learning disorder that involves difficulty reading due to problems identifying speech sounds and learning how they relate to letters and words (decoding). Also called a reading disability, dyslexia is a result of individual differences in areas of the brain that process language.


Though there's no cure for dyslexia, early assessment and intervention result in the best outcome. Sometimes dyslexia goes undiagnosed for years and isn't recognized until adulthood, but it's never too late to seek help.


Signs of dyslexia can be difficult to recognize before your child enters school, but some early clues may indicate a problem. Once your child reaches school age, your child's teacher may be the first to notice a problem. Severity varies, but the condition often becomes apparent as a child starts learning to read.


Children who have dyslexia are at increased risk of having attention-deficit/hyperactivity disorder (ADHD), and vice versa. ADHD can cause difficulty keeping attention. It can also cause hyperactivity and impulsive behavior, which can make dyslexia harder to treat.


I have been thinking for quite a while now of painting the plywood subfloor of my very large kitchen/dining room floor with something like the Rustoleum Home Floor Coating system. The cure time says 3-7 days, but that is impossible for my 3-adult household as this very high traffic room is also a walk-through to a bedroom/bath area with no other access. What can I do? Would covering the floor with kraft paper help? Or are there any other paint options out there?


Just came across this article and found it very useful! I too was impatient and started using a piece I just repainted as a side table and noticed it has marks on it now (clearly paint + polycrylic has not cured yet). Is there anything I can do to fix this? Should I reapply another coat of polycrylic? Any tips would be appreciated!


Two questions, when layering different paints, and allowing them to completely dry but not cure between would you expect the cure time of the finished project to be that of the topcoat or whatever the longest cure time is of all the products, primer, paint, glaze for example. Also, if adding a decorate finish which requires the use of painters tape, using the delicate surface painters tape would you have to wait until the topcoat layer the tape is applied to is completely cured or just completely dried? i.e. will delicate painters tape ruin uncured pain project below?


This was a wonderful article to read about dry and cure times. I just painted my living room hard wood floor with a porch and floor latex paint. Before I apply the clear polyurethane coats, do i need to let the paint cure or just dry. Thanks.


Hi Michele! The issue is a damp atmosphere can prolong dry/cure times. If you are taking hot steamy showers that could slow the dry and cure time down. That said it may be beneficial to strip and repaint. It sounds like the paint did not adhere 100% if you can scratch and see the wood. Lightly sanding the wood to create tooth and using a good primer should help the paint fuse 100%.


Thanks for the fingernail test Denise. I made a boo boo as per time wasted it seems. I used some old flat white zero voc paint VERY THIN COAT to prepare my wall for an expensive wallpaper I have arriving today via the net. Then I found out I should have not used it or I should have used a primer instead. It seems the cure time is 21-30 days, but most say a flat white zero voc thin coat can be wallpapered in 2 weeks. We shall see, I will use your fingernail test, thanks bunches dear.


P.S. What do you think, a thing zero voc dead flat coat with fans in the room should cure quicker than most paints ? Well, the thumb test will have to be my guide. Seems I put myself in at least a 2 week hole, LIVE & LEAN LOL.


Does this apply to homemade chalk paint as well? Just finished painting two coats (24 hours apart) on a foyer cabinet. Need to seal with Polycrylic. Wait until cured? Or just dry? Thank you for clarifying,


Most squamous cell carcinomas (SCCs) of the skin can be cured when found and treated early. Treatment should happen as soon as possible after diagnosis, since more advanced SCCs of the skin are more difficult to treat and can become dangerous, spreading to local lymph nodes, distant tissues and organs. Find out more about treatment options for advanced or recurring SCCs here.


The physician scrapes or shaves off the SCC with a curette (a sharp instrument with a ring-shaped tip), then uses heat or a chemical agent to stop the bleeding and destroy remaining cancer cells. The procedure may be repeated a few times during the same session until no cancer cells remain.


The ultimate herpes cure may not come from a shot or an ointment. It may actually come from genome editing. It sounds like science fiction, but modern technological advances have brought us closer and closer to altering the DNA sequences of humans.


In December 2019, scientists from Harvard Medical School successfully disrupted the herpes simplex virus for the first time and identified weak spots where the virus may be susceptible to gene editing. However, that accomplishment is only the beginning of the process for a CRISPR herpes cure.


Until a herpes cure becomes a reality, you can still use current herpes treatments to manage outbreaks. From at-home DIY measures and online pharmacies to supplements and topical remedies, you have plenty of options to consider.


You can also use Hard Gel without a colour coat for a natural finish. For this look, simply apply Base Coat, 2 coats of Hard Gel and then your Top Coat. We love this look using our pink of soft clear pink Hard Gel for a super quick manicure that looks effortless.


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